Irreplaceable You— Full Cast

Gugu Mbatha-Raw

as Abbie

Michiel Huisman

as Sam

Steve Coogan

as Mitch

Timothy Simons

as Dominic

Jacki Weaver

as Estelle

Kate McKinnon

as Glass Half Full Kate

Christopher Walken

as Myron

Zach Cherry

as Jim

Jessie Ennis

as Melanie

Glenn Fleshler

as Mean Phil

Zabryna Guevara

as Dr. Michaelson

Brian Tyree Henry

as Benji

Rick Holmes

as Dr. Kessler

Alanna Masterson

as Sally

Gayle Rankin

as Mira