Splice— Full Cast

Adrien Brody

as Clive

Sarah Polley

as Elsa

Delphine Chanéac

as Dren

David Hewlett

as Barlow

Abigail Chu

as Young Dren

Stephanie Baird

as Elsa / PD

Brandon McGibbon

as Gavin

Amanda Brugel

as Melinda Finch

Simona Măicănescu

as Joan Chorot